1. The Bioinformatics Support Program provides three workstations to NIH staff that offer access to licensed and open source bioinformatics software programs. These workstations, located in the main reading room, are dedicated to high-throughput data analysis such as next generation sequence (NGS) data analysis or microarray data analysis.
  2. Chromas is free of charge. The PeakTrace RP component requires registration for a free account, and is a paid service after the 40 free units have been used. An introductory discount is available by following the link under the Options menu in Chromas. If you need to assemble multiple overlapping sequence reads, please see ChromasPro.
  3. MEGA 11 (64-bit) (for macOS) MEGA is provided FREE for use in research and education (see terms below) To download MEGA, please fill in the information requested below about how and where MEGA is used. This anonymous information is important for obtaining funding support for the maintenance and further development of MEGA.
  4. SnapGene Viewer is revolutionary software that allows molecular biologists to create, browse, and share richly annotated DNA sequence files up to 1 Gbp in length. What are the differences between SnapGene and the free SnapGene Viewer?

Products

Sanger/short contig bioinformatics tools

DNA Sequence Assembler

DNA Sequence Assembler is unique and revolutionary bioinformatics software for

  • manual DNA sequence assembly
  • automatic DNA sequence assembly
  • DNA sequence analysis
  • batch file format conversion (SCF, ABI, FASTA, SEQ, TXT, GBK)
  • mutation detection
Chromatogram Explorer Lite

Mq trainer with nova gem hack free. Allows quick DNA sequence inspection:

  • Display sample's content as you browse through your folders
  • Highlight low quality regions
  • Manually or automatically trim low quality ends (batch)
  • Convert between miscellaneous formats
  • View FASTA, SEQ, TXT, SCF, ABI, AB, AB!, AB1 samples
  • View sample properties & statistics
  • Display confidence scores

Freeware

Sanger Sequence dereplicator

Clone Library Dereplicator simplifies the dereplication of all type sequence libraries (16S rRNA, 18S rRNA, 23S rRNA, 28S rRNA, functional and structural proteins) and prepares the raw sequences for subsequent analyses or contig assembly. Clone Library Dereplicator sorts all unique DNA sequences (FASTA) belonging to your clone libraries, by moving/coping them into the specified folder.

Freeware

Cell counter

Cell Counter is a freeware tool that will help you to manually count the cells shown on computer screen by displaying a transparent or semi-transparent grid over your image.

Freeware

To get your free 15-day evaluation license or to update your version of Sequencher to 5.4.6, follow these four easy steps. This will provide you with the full Sanger and NGS functionality for your DNA Sequencing. Step 1: Download. Step 2: Download. Note: GSNAP is 64-bit only in Sequencher 5.4.

NextGen bioinformatics tools


NextGen Sequence Analyzer

An efficient and easy to use FastQ/SFF viewer, editor, filter and converter. NextGen Workbench is the first and the only complete FastQ/SFF editor with graphic interface on the entire bioinformatics market! The program can process huge FastQ/SFF files even when running o a modest computer. Freeware

  • Delete samples; cut a file in smaller pieces
  • Convert from FastQ/SFF to multiFASTA format
  • Sort samples by name, average quality and length
  • Displays info: number of samples/reads, average quality of each sample, sample length, mini-chromatograms, clipped ends
  • Compact and portable (no installation required)

Sequence Dereplicator is a graphic interface tool that allows you to dereplicate your Fasta sequences via sequence clustering.

Freeware

Size: 2 MB

Avalanche Workbench

Avalanche Workbench is a visual data analysis & DNA sequence data mining tool for biologists.

It offers a visual graphic interface through which you can search (eSearch, eLink, eSummary, eFetch) biology databases such as NCBI or get visual access to sequence processing tools/servers.

Freeware

Fasta/FastQ merger

Merge two or more large sequence files (fasta, fsa, fast, fastq, seq, gbk, etc).

Freeware

NCBI suite


A tool that automatically downloads and installs the latest NCBI Blast+ edition in your computer.

Freeware

NCBI Blast DB Downloader

A tool that automates the NCBI BLAST DB download process. It automatically downloads and unpacks the selected NCBI Blast databases from NCBI ftp server.

Freeware

NCBI Database Builder

A tool that allows you to create Blast databases from your own Fasta files.

Freeware

Other tools

DNA Baser console

This is a the command line version of DNA Sequence Assembler. Now you can harness the power and accuracy of DNA Baser at a new level by performing custom sequence assembly from your very own scripts.

BaserConsole.exe ^
/InputFolder='c:samples' ^
/FileType='*.scf' ^
/OutputFolder='c:samplesout' ^


pause > nul

PolyPro - Polynucleotide probe designFreeware

In situ hybridization of genes and mRNA is most often based on polynucleotide probes.

We recently developed a concept and software (PolyPro) for rational design of polynucleotide probe mixes to identify particular genes in defined taxa. PolyPro consists of three modules: a GenBank Taxonomy Extractor (GTE), a Polynucleotide Probe Designer (PPD) and a Hybridization Parameters Calculator (HPC).

Convertrix - A Batch DNA Sample Converter

Convertrix is a molecular biology command line tool for converting between several popular DNA sample formats. It can automatically trim the untrusted regions (low quality bases) at the end of samples. The program needs no manual: a graphic interface is available to help you to generate the command line.

Date of release: April 2010

Everything to FASTA converter

Everything to Fasta Converter converts at batch the samples (SCF, ABI, FASTA, multiFasta, GBK, multiGBK, SEQ, TXT) to FASTA format. Protein FASTA files are also supported.

Freeware

GBK to FASTA converter

GenBank to FASTA converter is a a freeware molecular biology tool that can convert GenBank (gb/gbk) file format to FASTA format.

Freeware


DNA Nucleotide Counter

DNA Nucleotide Counter is a freeware tool that shows the proportions between nucleotides (A, C, G, T, CG, AT) in a DNA sequence. Compact and easy to use.

Freeware

Sequence Analysis Viewer

Free

Installs in any computer!

Our bioinformatics software tools can be installed in any Windows computer and it works properly EVEN IF YOU DON'T HAVE ADMINISTRATOR RIGHTS. In this case just install the program somewhere else than Program Files; for example in a folder where you have write permissions such as 'c:MyPersonalFolder', 'Desktop' or 'My Documents'.

Portability

Our software tools are really small so you can easily copy them on a floppy disk or USB flash stick and take them with you or send them to your colleagues via email.

Quick links

Professional DMX Lighting Control.
Mac Style.
  • Highly Compatible.

    Bring your own DMX interface: USB, Art-Net, sACN, or ESP-Net.

  • Vastly Powerful.

    Lightkey’s built-in FX engine takes your light show to a new level.

  • Surprisingly Simple.

    Easy to learn, quick to set up. Engineered exclusively for Mac.

Highly Compatible.
Bring Your Own DMX Interface.

Software

Save the cost of expensive proprietary DMX hardware: Lightkey works with a wide range of USB interfaces plus any Art-Net, sACN, or ESP-Net-compatible device, thanks to the Open Lighting Architecture. Whatever DMX interface you have, there’s a good chance that Lightkey supports it—simply download Lightkey for free, plug in your interface, and give it a try.

Choose from a wide range of USB–DMX interfaces from various manufacturers

Or use any Art-Net, sACN, or ESP Net network interface

Show Supported InterfacesHide Interfaces

Hardware Control.
Enhance Your Experience.

Do you prefer the physical controls on a lighting console? Then you can have the best of both worlds. Lightkey integrates seam­lessly with any standard MIDI controller and DMX console (through DMX-In). You can map each hardware control to whatever feature you like and build your own custom-tailored show control desk to trigger cues, presets and sequences, adjust fixture properties, tap the beat, and whatever else you need.

Designed for Creativity.
Take Your Light Show to a New Level.

Designed for the needs of creative lighting designers, Lightkey breaks free from the old thinking about DMX values and channels. Thru advanced fixture profiles it understands all your fixtures’ properties—like Color, Gobo, Shutter, Prism, Zoom—, and provides specially-designed, easy-to-use controls for each of them. The current state of your fixtures is always visible in the live preview. Simply concentrate on the perfect light show and let Lightkey translate it to the proper DMX values.

  • Virtual Light Beams

    Virtual light beams show your lights’ real-world positions and also reflect intensity, color, focus, zoom, iris, frost, and shutter/strobe states.

  • Built-In Stage Editor

    The built-in graphical editor lets you recreate the stage or dance floor on the screen. Apart from your fixtures you can add shapes, trusses, and custom images.

  • Copy & Paste

    Easily copy and paste properties and effects between fixtures – even fixtures of different types. Of course, you can undo as well.

  • At a Glance

    Little “bubbles” in the Preview show you at a glance which fixture properties are overridden or defined by a preset, sequence, or cue.

  • On-the-Fly Changes

    Quickly change any fixture property on the fly—perfect for nightclubs and parties where you don’t have a song run sheet in advance.

  • Intelligent Design View

    The Design view automatically adapts itself according to your fixtures and their properties so you only see the controls you really need.

Real-World Pan/Tilt Locations

Lightkey knows your moving light’s pan/tilt range, home position, and rotation direction. With this information it calculates the exact beam position on the stage or dance floor, so the preview always shows the fixture’s real-world position, letting you point your lights wherever you like with just a single mouse click. Even if you select multiple devices from different manufacturers, Lightkey will calculate the individual DMX values for each of them so they all point in the same direction.

Effects.
Infinite Possibilities.

Lightkey’s powerful effects engine makes it easy and fun to create amazing dynamic looks. Choose from over 50 effect templates or create your own pattern, curve, or movement effects. Effects can be applied to almost any fixture property and stored in presets and cues while staying editable all the time. Apply effects to multi-beam LED strips and matrixes. Synchronize effects to music. Overlay multiple effects for countless possibilities.

Beat Control.
Stay in the Rhythm.

Effortlessly sync your light show to music. Lightkey connects to your DAW, DJ app, or audio analysis software through MIDI Clock or Ableton Link. Or simply tap the beat and Lightkey will continue at the same tempo. You can adjust the speed of individual cues at any time with a Beat Multiplier.

  • Tap the Beat

    Tap the beat with the mouse, keyboard, or a MIDI controller, and Lightkey will pick up the tempo.

  • MIDI Clock

    Receive a MIDI Beat Clock signal sent by a DJ software, mixer, or audio analysis tool.

  • Ableton Link

    Ableton Link syncs beat information between apps on the same computer or local network.

Always in Sync.
Run Your Lighting From Ableton Live.

The unique Live Triggers feature makes it quick and intuitive to trigger lighting cues directly from Ableton Live: Simply drag cues you created in Lightkey to the Ableton Live timeline. If you’re a live performer, you can create a light show that’s perfectly in sync with the music without any manual operation during the show.

Setup.
Surprisingly Simple.

An interactive assistant guides you through the entire setup process: Configure DMX output, patch your fixtures, create a visual representation of the stage. And if you ever need a fixture profile that is not in the built-in library, simply send us the DMX specs and we’ll create it for you within a few days.

Live Preview
This 2D view of your lighting rig shows the current state of the fixtures with virtual light beams
Preset Palette
Create and organize presets and sequences
Control panel
Build a custom-tailored control panel with buttons and faders to control your lights during a show
Shortcuts
Shows keyboard shortcuts and gestures for the current context

Command Central.

Don’t waste your time shuffling windows and panels around. Everything you need is cleanly arranged in a single window, providing you with exactly the controls you need at any time. The elegant, white-on-dark UI has been specially designed for use in low-light environments—it even adapts itself to the light colors.

Sequence Analysis Software Free Mac

  • Full-Screen Mode

    The single-window user interface has been specially designed for full-screen mode.

  • Touch Screen Support

    All controls have large clickable areas and work great with touch screens.

  • Multi-Touch Gestures

    Pinch, swipe, scroll, force click: With a Multi-Touch trackpad you can change fixture properties in a natural way. (And it’s fun too.)

  • Extensive Keyboard Shortcuts

    A clever, well-structured, and extensible system of keyboard shortcuts lets you control virtually every application feature.

Lightkey User Guide.
Take an in-depth look.

Fixtures.
State of the Art.

Lightkey handles even the most sophisticated fixtures with ease. Its smart fixture profiles support multiple modes (“personalities”), 16-bit output, conditional properties, RGB/CMY color mixing, multiple color and gobo wheels, custom beam layouts, and much more. Lightkey comes with a huge library of over 3000 high-quality fixture profiles for all popular manufac­turers, and it can import thousands of freely available profiles in the formats SSL2, FXT, and PFF.

Sequence Analysis Viewer Download

Built-In Fixture Editor

To make fixture profile creation as easy as possible, Lightkey’s fixture editor has the same layout as a typical DMX chart. (Click the image for a side-by-side comparison.) And it’s built right into the application so changes take effect instantly.

Lightkey’s fixture editor (right) has the same layout as a typical DMX chart (left).

High Technology.
Made for Your Mac.

Lightkey was engineered from the ground up as a native Mac app, so it’s finally goodbye to the Windows emulation. It perfectly matches your Mac’s look and feel and comes with all the familiar features like Dark Mode, full screen view, autosaving, copy and paste, unlimited undo, or automatic updates. Under the hood, Lightkey takes full advantage of your Mac’s capabilities including 64-bit processing on M1 and Intel chips, multicore computing thru Grand Central Dispatch, support for Retina displays, and pristine graphics using Apple’s Core Animation and Metal 2 technologies.

Pristine Retina graphics
powered by Metal 2
Haptic feedback, multi-touch gestures and force click

Editions & Pricing.
What’s Your Lightkey Edition?

Simply determine how many output channels you need.
  • All editions come with the full feature set, even the free edition.
  • You can always upgrade if you need more channels later.
Output Channels
256
1024
Price
in US Dollars,
taxes may apply
$ 79per year
$ 199per year
USB Output
Art-Net Output
sACN Output
ESP-Net Output
Live Triggers
DMX Input
MIDI Input
Free Tech Support

Check it Out.
Today. For Free.

Download Lightkey today and see for yourself. It’s free, easy, and a great deal of fun.
Download Lightkey

What You Need

Lightkey is powered by the Open Lighting Architecture, an open-source framework by the Open Lighting Project.
Download the source code here or grab the latest version on GitHub.